Alphenyx
Alphenyx, Speeding up your discoveries. From Tissus to Cells.

 

Products

 

Human bio-specimens (tissues, cells and body-fluids) are required for many research purposes.
Alphenyx has therefore established a broad tissue acquisition network to obtain normal and diseased human-origin tissues and body fluids in accordance with the latest European guidelines.

Alphenyx products are designed for use in efficacy and safety testing of new compounds. We specially developed specific devices to transform raw tissues into standardized high-quality products. Alphenyx products are for research use only.

Skin derived Products:

 

    Tissues: Adult Skin

    • Adult skin (abdominal, breast, ...)
    • Different customized formats or disks (8mm to 30 mm diameter)
    • Full-thickness or dermatomized (up to 750µm thickness)
    • Fresh or Frozen.


    Donor information includes age, sex, ethnicity, BMI and treatment.

    Skin products could be selected on the fresh explants before its preparation.

    Thickness of dermatomized skin discs is controlled individually by a specific system. Mean, min and max data are reported on the data sheet for each disc individually.

     

    Cells: Adult Normal Skin Cells:

    All our cells are isolated from fresh tissues. Cryopreserved cells are supplied in batches of 500 000 cells per vial. Cells are at low passage (P0 to P2, depending on the cell type).

    • Human Epidermal Keratinocytes (HEK)
    • Human Epidermal Melanocytes (HEM)
    • Human Dermal Fibroblasts (HDF)
    • Human Adipose Derived Stem Cells (hADSC)
    • Human Subcutaneous Pre-Adipocytes (HPAd)
    • Human Sebocytes available soon!!!!!


    Cell purity and biological function(s) are systematically tested via flow cytometry.

    All our cells are tested for absence of mycoplasma, bacteria, yeast and moulds before cryopreservation.

    Other skin products:

    • S9 fraction for metabolism studies

     

    Blood derived Products:

     

    Adult Normal PBMCs

    PBMCs are isolated from fresh blood from adult donors in collaboration with EFS (Etablissement Français du Sang).
    Cryopreserved cells are supplied in batches of 10 000 000 cells per vial for total PBMCs.
    Bulk isolation is also available on request.

    Cell subtype

    Cell subtype isolation is performed on demand from fresh or cryopreserved PBMCs by magnetic cell sorting (negative, positive or sequential). FACS-based sorting is also available on request.

    • CD19+ B cells
    • CD4+ helper T cells
    • Regulatory CD4+ T cells
    • CD8+ cytotoxic T cells
    • CD56+ NK cells
    • Dendritic cells
    • CD14+ monocytes…..

    Other blood products

    • Serum or plasma
    • Total human immunoglobulin

Cell purity and biological function(s) are systematically tested via flow cytometry.

All our cells are tested for absence of mycoplasma, bacteria, yeast and moulds before cryopreservation.